Former Boro midfielder Gary O’Neil is a doubt for Bolton after coming off in the first half of Saturday’s 2-1 defeat to Ipswich Town. Another former Boro midfielder, Yanic Wildschut is also likely to miss out with an ankle injury.
Jack Hobbs, Luke Murphy and Jason Lowe are also unavailable for Bolton heading into the game.
George Friend suffered a hip injury against Swansea City on Saturday and is a concern going into the trip to Bolton.
Lewis Wing will also miss out on the trip after requiring an operation on his hernia which could rule him out for the remainder of this season.
Boro fans will be able to purchase tickets on the turnstiles of the University of Bolton Stadium.
Both teams are desperate for three points, with Bolton requiring a boost in their bid to avoid relegation, while Boro are looking to put their run of six defeats behind them. However the stats don't look good for Boro boss Tony Pulis, having never won away from home against Bolton in a league match.